Season twelve of  ‘ South Park ‘ shown to the public on March 12, 2008. The season ended on November 19, 2008.

Cartman gets HIV when his tonsils were taken out. He tries to find a cure for AIDS. He also tries to pass his illness to Kyle, since Kyle made fun of him.. Kenny acquires a weird addiction of the scent of cat urine, and this bothers the rest of the gang. Cartman gets all the cats in town and Kyle’s father becomes addicted to cat urine smell as well. The nation goes into a strike over money acquired in the Internet, as headed by the World Canadian Bureau (“WGA” for short) leader. Butters is made to become the viral video star by the boys. Mrs. Garrison becomes Mr. Garrison again, having reversed her sex change. Cartman gets a job as a teacher in a school at the city. When the Internet connection in South Park disappeared, the residents were gravely worried. When the kids of South Park Elementary School were about to go to a living museum, Cartman sneaks to the amusement park instead with Butters. The rest of his schoolmates became hostages in the museum. The two of them also go to P.F. Chang’s, for Cartman believed that Chinese will take over America. After seeing the most recent Indiana Jones movie, Stan, Kyle and Kenny find themselves in trauma. Wendy becomes annoyed with Cartman’s insult towards her report on breast cancer. The boys find out the secret about the attack of the giant guinea pigs when they were in the Andes Mountains. For the 2008 US presidential elections, Barack Obama acquires supporters from South Park. These supporters of his celebrate for his triumph. Meanwhile, at the elementary school of South Park, High School Musical becomes a fad, as well as the movie “Twilight.” Butters think that the vampire fans are authentic vampires and actually considers being one of them.